Prime Minister Andy Burnham will officially open his new northern administrative hub in Manchester on Friday as part of a wider effort to shift power away from central London.
The facility, named Number 10 North, is designed to serve as a regional base for government operations and economic planning.
The announcement comes shortly after Andy Burnham took office at Downing Street on Monday following the departure of Keir Starmer.
Speaking ahead of the opening, the prime minister reiterated his commitment to spreading economic growth across all regions of the country.
Andy Burnham stated that for four decades, London had concentrated national resources, leaving many local communities feeling overlooked.
He expressed confidence that the new facility would help local authorities turn around their regional economies.
The Prime Minister intends to work from the Manchester site at least one day each week, with his office describing the location as a situation room for growth.
The initiative draws on his nine years of experience as mayor of Greater Manchester, where the city-region achieved higher economic growth rates than the national average.
As part of the operational setup, departments including the Treasury will transfer overarching strategic functions to the new hub.
Number 10 North will operate within the newly established Office for the Prime Minister and the Cabinet, headed by civil service chief Antonia Romeo.
The Prime Minister is also re-establishing the National Economic Council, a body first set up in 2008 during the global financial crisis.
He will chair the council's first meeting at the Manchester hub on Friday alongside senior government ministers and regional mayors.
However, constitutional experts have raised questions about whether the move constitutes genuine devolution of power.
Policy adviser Alan Trench noted that shifting administrative functions represents de-concentration rather than a true transfer of legislative authority to local communities.
Academic Nicola McEwen welcomed the strategic role given to the office, noting that its success depends on working closely with devolved administrations in Scotland, Wales, and Northern Ireland.
Meanwhile, political scientist Michael Keating cautioned that creating a new central department in the north may not fully balance the financial authority held by the Treasury in London.
